37 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Amy Chung, MD, MSc ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Carpal Tunnel Syndrome: Pathogenesis and clinical findings
 • Dysthesias - Tingling, burning, or painful sensation at
Carpal Tunnel Syndrome ... pain at 1st 3.5 digits ... #CarpalTunnel #Syndrome ... #pathophysiology ... #msk #overuse
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... proprioception, and light ... #diagnosis #pathophysiology ... signs #symptoms #msk ... #orthopedics #neurology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... medial half of 4th digits ... CubitalTunnel #Syndrome ... #Diagnosis #pathophysiology ... signs #symptoms #msk
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
infiltration • Light ... change disease • Hematologic ... Capillary leak syndrome ... • Tumor lysis syndrome ... Classification #Nephrology
Marcus Gunn Pupil - Relative Afferent Pupillary Defect (RAPD)
Definition: Afferent loop of the pupillary light reflex
the pupillary light ... neuritis due to MS ... Later (1959), Levitan ... with the swinging light ... #Defect #RAPD #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Leukostasis: • Pathophysiology ... : • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... , asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Principal patterns of loss of sensation.
 (a) Thalamic lesion: sensory loss throughout opposite side (rare).
temperature loss but light ... Brown—Séquard syndrome ... MS: loss of proprioception ... vibration and light ... #Diagnosis #Neurology