15 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
DADS-M, Sporadic, late-onset ... Type I cryo GN, Light-chain ... deposition disease (light ... #Significance #MGUS ... #oncology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
MGCSMGRS ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
corresponding light-chain ... appropriate involved light ... amyloidosis • Rate ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Causes of false- ... (1-2% of MM), light ... #Gammopathies #MGUS ... #diagnosis #hematology ... #oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... thrombosis; PE = pulmonary ... glomerular filtration rate ... Anticoagulation #Management #Hematology ... #Oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... : 33% • Treatment ... CKD, CHF, high rate ... , and CXR with pulmonary ... : No • Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... degrees • Chills, night ... CXR upright or lat ... Lung #Abscess #pulmonary
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
crackles in the right ... epilepticus • Pathophysiology ... Edema: • Pathophysiology ... decreased respiratory rate ... • Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... Imaging: CXR- pulmonary ... Renal Failure Treatment ... #oncology