14 results
diagnosis differential monoclonal acute cancer classification gammopathy injury leukemia management mgus significance syndromes aki apml chronic clinical cll differentiation disorders
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... of breath • Neurologic ... • Paraplegia (late ... : Tumor Lysis Syndrome
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... Differential #Diagnosis #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
infiltration • Light ... change disease • Hematologic ... Capillary leak syndrome ... #AKI #Cancer #Oncology ... Classification #Nephrology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... proprioception, and light ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Differential Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... seizures Life/sight-threatening ... #neurology #PHANTOMS
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... constitutional symptoms ... amyloidosis • Rate ... #Significance #hematology ... #diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology
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