27 results
diagnosis management differential oncology monoclonal signs classification disease erythematosus gammopathy leukemia lupus mgus significance sle syndromes systemic vasculitis workup acute
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Differential Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... • Schnitzler syndrome ... Differential #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
Malignancy - Night ... pain, night sweats ... splenomegaly, abnormal neurology ... cell disease Rheumatology ... #Limping #NWB #Algorithm
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... pattern of spread, B symptoms ... very high mitotic rate ... Classification #pathophysiology ... #Hematology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... proprioception, and light ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
blood donor • Pathophysiology ... ARDS to explain symptoms ... CKD, CHF, high rate ... transfusion • Pathophysiology ... Transfusion #Reactions #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
Differential Diagnosis Algorithm ... papilledema • Horner syndrome ... ) • Systemic symptoms ... seizures Life/sight-threatening ... #neurology #PHANTOMS
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... et diutinum Neurologic ... neuropathy) • Systemic late-onset ... • Crystalline: light ... Paraproteinemias #Hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Summary Framework Hematologic ... sub-types based on the hematologic ... constitutional symptoms ... amyloidosis • Rate ... #Significance #hematology
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