74 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... Risk factor for Late ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... Pathogenesis and Clinical ... T lymphocytes also ... the etiology Signs ... GravesDisease #pathophysiology
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
inflammatory cells) Clinical ... : • Disease fatal ... exertion • Neurologic ... dysrhythmias • Ophthalmologic ... #Signs #Pulmonary
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Diagnosis Algorithm Symptoms ... Fatigue, Pruritus, Right ... quadrant discomfort Signs ... of autoimmune disease ... Elevated ALP 2.
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... and Late Clinical ... • Heralded by neurologic ... #diagnosis #signs ... #symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... proliferation rate ... diagnosis #management #hematology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
Pathogenesis and Clinical ... disease progresses ... spinal column) • Late ... #diagnosis #signs ... #symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... • Jaundice (later ... diagnosis #workup #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... body, but can also ... Noncontiguous spread • Clinical ... Lymphomas • Other hematologic ... #differential #hematology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... gene mutated in all ... Retinoblastoma #pathophysiology ... #ophthalmology ... #symptoms