44 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... • JC-virus PCR sensitivity ... effect/Edema • EBV ... analysis has a sensitivity ... #Infections #differential
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
CNS Ring-Enhancing ... + toxo IgG • CNS ... granulomatosis: • EBV-associated ... 30% present w/ CNS ... Lesions #Brain #differential
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Hypernatremia - Differential ... Malignancy - CNS ... Insipidus (Incr ADH sensitivity ... Hypernatremia #Differential
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... epidermal turnover rate ... accelerated mitotic rate ... Nikolsky #Algorithm #Differential
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... Short Stature (Late ... Anorexia Nervosa • CNS ... #ShortStature #Differential
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Heat Stroke - Differential ... Collapse: • Pathophysiology ... Decreased pulse rate ... CNS dysfunction ... heat #illness #differential
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... CSF has a 99% sensitivity ... with a diagnostic sensitivity ... Singh @rav7ks #CNS
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
neuropathy) • Systemic late-onset ... Scleromyxedema (CNS ... +GI+CVS+joints) ... +PNS+GI+Endocrine ... Hematology #Monoclonal #Differential
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
three primary pathophysiologic ... Henoch-SchonIein Purpura Anti-GBM ... to Kidney: Anti-GBM ... involvement: Anti-GBM ... Glomerulonephritis #Vasculitis #differential
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Disease: Early and Late ... Localized • EM ... days-weeks after EM ... lymphocytic meningitis, CN