32 results
NSAID vs ACEI/ARB effects on the Kidneys

Remember that NSAIDs and ACEI/ARB therapy have opposing effects on
effects on the Kidneys ... NSAIDs cause vasoconstriction ... use shouldn't cause ... ACEIARB #Effects #Nephrology ... #Renal #Pathophysiology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
Acute Kidney Injury ... Glomerular (red blood cells ... biopsy - Management ... treating underlying cause ... appropriate) #Acute #Kidney
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
- Diarrhea • RENAL ... smooth muscle cells ... unloading • Kidney ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Distal Renal Tubular Acidosis (RTA)  Type 1 

Totally scuppers the kidney's acidification mechanism. Will be
Distal Renal Tubular ... Totally scuppers the kidney's ... Distal #Diagnosis #Management ... #Nephrology #Causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Summary Causes ... nephrotoxicity to kidney ... tubular cells ... #nephrology
Hyperuricemia: Pathogenesis and Complications

 - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
of calcium in renal ... decr ability of kidneys ... WBCs, and skin cells ... Release of purine bases ... Hyperuricemia #Pathophysiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Agents Regulating Renal ... irrigation • Management ... stones caused by ... Inhibitors of Renal ... Excretion #Diuresis #Nephrology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Bleeding (64%) • Renal ... Treat primary cause ... #treatment #management ... #hematology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... collection with EDTA Pathophysiology ... neuropathy • Renal ... : - Renal failure ... Phosphatase: • Other causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology