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differential hematology infectiousdiseases management anemia aplastic apml cardiology chronic cll dermatology differentiation emergencies endocarditis hantavirus hemeonc intermittent leukemia lymphocytic oncologic
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... endocarditis, malaria • Leptospira ... • Leptospirosis ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... • Prodrome: fever ... +/- diarrhea Diagnosis ... #microbiology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Upper respiratory infection ... gastrointestinal infection ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... /fevers • Thrombocytopenia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... : - Fever + ANC ... if SSTI or port infection ... abdominal pain; full infectious ... #HemeOnc #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... : Infection (sepsis ... management #hematology #oncology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
region Viral Syndromes ... ; dengue shock syndrome ... capillary leak syndrome ... : • Leptospirosis ... Zika virus or leptospira
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... weeks without infection ... lymphocyte > 5000/microL ... microglobulin Treatment ... #workup #oncology
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
Hypercoagulable (APLAS) Microbiology ... night sweats, fever ... Cholesterol emboli syndrome ... hematuria, + RF Treatment ... Persistent bacteremia/fevers
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