137 results
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... non-productive cough, nausea ... Epidemiologic exposure + clinical ... #Leptospira #microbiology ... #diagnosis #treatment
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
BPM INFECTIOUS CAUSES ... • Malaria • Leptospirosis ... OTHER CAUSES ... CLINICAL UTILITY ... #differential #causes
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
• Rickettsial diseases ... • Crohn disease ... Non-Infectious Causes ... • Leptospirosis ... • Malaria • Leptospirosis
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness of Leptospirosis ... develop severe disease ... -14 days): • Fever ... rash • Others: nausea ... Questions @WuidQ #Leptospirosis
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Bradycardia Cardiac Disease ... • Chagas disease ... Babesiosis • Leptospirosis ... Spondylarthropathies Other causes ... differential #diagnosis #causes
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... most common) Clinical ... to rnonths • Fever ... , hemoptysis Treatment ... Diagnosis #Pulmonary #Clinical
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
barns and lake houses ... • Prodrome: fever ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... of Fever CRITICAL ... - Sickle cell disease ... Sarcoidosis - Crohn disease ... Noninfectious #Causes
Doxycycline - Coverage and Indications
 • Staphylococci (S aureus + CoNS)
 • The tick stuff: Borrelia
Borrelia (Lyme disease ... • "Atypical" causes ... Bartonella, Q fever ... #pharmacology #microbiology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess - Clinical ... : • 80% have fever ... Intervention: - Fevers ... #differential #causes