33 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Symptomatic anemia Diagnosis ... if neutropenic fever ... progress to MDS or acute ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... presents as an acute ... following: • Fever ... : • Infection ... #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... triad: Fever, Arthralgia ... : • Infectious ... #management #treatment ... #rheumatology
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
respiratory symptoms • Fever ... pulmonary symptoms • Rheumatologic ... has five major clinical ... • Cough, fever ... fungal stain of clinical
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : • Common: fever ... : Infection (sepsis ... Renal Failure Treatment ... #management #hematology
Acute Dacryocystitis- A 4-week-old boy was brought to the emergency department after having drainage from both
He received a diagnosis ... — infection of ... agents, and the fever ... #NEJM #clinical ... #photo #peds #acute
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Mild: Malaise, fever ... Acute myocarditis ... • Treatment: ... useful for chronic infection ... #Management #Microbiology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... : 33% • Treatment ... At least 3 of (Acute ... : No • Treatment ... #diagnosis #comparison
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... Presentation: Fever ... nephrotic syndrome, or acute ... hypertension and acute ... Syphilis #stages #diagnosis