68 results
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Leptospirosis Pathogen ... failure • Severe pulmonary ... manifestations • MAT microscopic ... #Leptospira #microbiology ... #diagnosis #treatment
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... infarction - Pulmonary ... Neuroleptic malignant syndrome ... Postmyocardiotomy syndrome ... #Causes #Differential
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... - Differential Diagnosis ... other hemorrhagic fevers ... , Leptospirosis, ... #Differential #Diagnosis
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
- Differential Diagnosis ... Hyperkalemia Pulmonary ... Babesiosis • Leptospirosis ... #differential #diagnosis ... #causes #cardiology
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Leptospirosis ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... to rnonths • Fever ... , hemoptysis Treatment ... Lung #Abscess #Diagnosis ... #Pulmonary #Clinical
Non-Resolving Pneumonias: Etiologies
Unusual Infections:
 - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia)
 - Endemic Fungi (e.g.: Histoplasmosis,
psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... polyangiitis, microscopic ... Others: - Pulmonary ... NonResolving #Pneumonia #diagnosis
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
Cardiopulmonary Syndrome ... • Prodrome: fever ... +/- diarrhea Diagnosis ... #management #treatment ... #microbiology #
Biphasic Illness of Leptospirosis
Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness of Leptospirosis ... -14 days): • Fever ... rash • Others: nausea ... dysfunction) • Pulmonary ... Biphasic #Phases #Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Cough, Dyspnea, Fever ... Differential Diagnosis ... polyangiitis, Microscopic ... #differential #diagnosis