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management differential infectiousdiseases rheumatology causes hematology infections lung nephrology algorithm cardiology clinical oncology renal summary syndromes dermatology tb tuberculosis vasculitis
Leptospirosis Pathogen: Leptospira (interrogans, kirschneri, noguchii) Risk Factors: • Occupational exposure - Farmers, ranchers, trappers, veterinarians • Recreational
failure • Severe pulmonary ... disease ARDS Diagnosis ... manifestations • MAT microscopic ... #Leptospira #microbiology ... #diagnosis #treatment
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... other hemorrhagic fevers ... , Leptospirosis, ... #Differential #Diagnosis
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... • Behcet's syndrome ... • Leptospirosis ... • Malaria • Leptospirosis ... #Differential #Diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Cough, Dyspnea, Fever ... Differential Diagnosis ... polyangiitis, Microscopic ... #differential #diagnosis
Differential Diagnosis - Noninfectious Causes of Fever CRITICAL DIAGNOSES: - Acute myocardial infarction - Pulmonary embolism or
infarction - Pulmonary ... Neuroleptic malignant syndrome ... - Sickle cell disease ... Sarcoidosis - Crohn disease ... Postmyocardiotomy syndrome
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
- Differential Diagnosis ... Hyperkalemia Pulmonary ... • Chagas disease ... Babesiosis • Leptospirosis ... #differential #diagnosis
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness of Leptospirosis ... -14 days): • Fever ... dysfunction) • Pulmonary ... Questions @WuidQ #Leptospirosis ... Biphasic #Phases #Diagnosis
Lung Abscess Microbiology: • Polymicrobial • Anaerobes (most common) Clinical: • Indolent symptoms that evolve
Lung Abscess Microbiology ... to rnonths • Fever ... , hemoptysis Treatment ... Lung #Abscess #Diagnosis ... #Pulmonary #Clinical
Non-Resolving Pneumonias: Etiologies Unusual Infections: - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia) - Endemic Fungi (e.g.: Histoplasmosis,
psittaci/avian, leptospirosis ... yersinia/rats, Q fever ... polyangiitis, microscopic ... Others: - Pulmonary ... NonResolving #Pneumonia #diagnosis
Rhodococcus - Microbiology Overview Microbiology: • Facultative, intracellular, nonmotile, non-spore-forming • Aerobic acid-fast gram-positive coccobacilli • Produces
Transmission (Zoonotic disease ... due to trauma Diagnosis ... Treatment: • ... #diagnosis #treatment ... #pulmonary #Bacteria
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