21 results
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
Disease: Jaundice + renal ... failure • Severe pulmonary ... manifestations • MAT microscopic ... #Leptospira #microbiology ... #diagnosis #treatment
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... other hemorrhagic fevers ... , Leptospirosis, ... Kumfer @AnnKumfer #Pulmonary ... #Renal #Syndromes
Lung Abscess
Microbiology:
 • Polymicrobial 
 • Anaerobes (most common) 
Clinical: 
 • Indolent symptoms that evolve
Lung Abscess Microbiology ... to rnonths • Fever ... , hemoptysis Treatment ... meropenem) #Lung ... Abscess #Diagnosis #Pulmonary
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Cough, Dyspnea, Fever ... Renal Syndromes ... polyangiitis, Microscopic ... #Renal #Syndrome
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Infections BRASH Syndrome ... Bradycardia • Renal ... Hyperkalemia Pulmonary ... • Yellow fever ... Babesiosis • Leptospirosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Renal Syndromes ... sparing of the lung ... #Renal #Syndromes ... diagnosis #management #treatment
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
to Eosinophilic Lung ... arthralgias, CV, renal ... Hypereosinophilic Syndrome ... #Eosinophilic #Lung ... #Diseases #pulmonary
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Presentation: Fever ... • Fever and weight ... diagnosis • Microbiologic
Capnocytophaga
Pathogen: Capnocytophaga
 • 9 species, C. canimorsus responsible for the majority of infections
 • Gram-negative rod,
SIow growing, Long ... • Cellulitis: Fever ... failure: CID, Renal ... Treatment: • 50% ... Capnocytophaga #canimorsus #microbiology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal