43 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... : Lupus (SLE), Systemic ... Primary Biliary Cirrhosis ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... Positive in 60-80% of cases ... : Chronic disease ... #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
; common in SLE, ... Dermatomyositis Anti-LKM (liver ... Primary biliary cirrhosis ... #diagnosis #table ... #rheumatology #
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... • Infiltrative diseases ... sarcoidosis) • Liver ... Veno-occlusive disease ... #causes #hepatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... #Summary #diagnosis ... #rheumatology # ... management
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm
 • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... Ulcerative Colitis • Liver ... Cirrhosis, NASH ... HIV, CMV, Hep B and ... spondylitis, RA, SLE
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Workup: - ANA ... : Chronic disease ... #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Cerebrovascular Disease ... autoantibodies that will cause ... Erythematosus #SLE ... #management #treatment
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... function test, ANA ... (e.g., SLE), anti-phospholipid ... disease), HBsAg ... #hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Liver ... cirrhosis • Congestive ... #Differential #Diagnosis ... #Algorithm #causes