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differential rheumatology management oncology systemic travel cirrhosis classification dermatology erythematosus hepatology infectiousdiseases lupus sle syndrome treatment vasculitis arthritis autoantibodies autoimmune
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Frequent Differential Diagnoses ... infection Cardinal Symptoms ... localizing signs ... or symptoms - Malaria ... #differential #diagnosis
Travel History - Clues to Infectious Disease Diagnosis in a Traveler • Where did you
to Infectious Disease ... Diagnosis in a ... → Leptospirosis ... Rabies, cat scratch fever ... Commercial sex worker
Biphasic Illness of Leptospirosis Some patients do not progress to severe disease. Others, rapidly develop severe disease
Biphasic Illness of Leptospirosis ... brief interval symptom ... -14 days): • Fever ... Biphasic #Phases #Diagnosis ... #Illness #Signs
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune disease ... skin thickening Signs ... and Symptoms: ... #diagnosis #signs ... #workup
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Malar rash 40% - Fever ... sclerosis, Still's disease ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Workup Summary Use a positive diagnostic strategy with minimal testing.
and Workup Summary ... last 3 months + symptom ... missing things" → fewer ... Rule out celiac disease ... inflammatory bowel disease
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
Disease: • Endemic ... Infections: • Leptospirosis ... cases of malaria diagnosed ... and myalgias, symptoms ... culture; rapid diagnostic
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
failure PBC Signs ... and Symptoms: ... but elevated as disease ... , IgG4 related disease ... #workup #hepatology
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