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differential management oncology algorithm rheumatology rash anemia alopecia clinical hairloss thrombocytopenia treatment aflp aplastic classification common comparison dermatomyositis diffuse hellp
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... Physical Exam/Signs ... Diagnosis: • ... • Richter’s Syndrome ... workup #oncology #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... ITP • SLE • CLL ... Non-lmmune: • HELLP Syndrome ... #Hematology
Erythematous Rashes - THE ALGORITHMIC APPROACH Characterized by diffuse redness of the skin due to capillary congestion, erythematous
the Nikolsky sign ... staphylococcal scalded skin syndrome ... and toxic shock syndrome ... or Nikolsky sign ... #Diagnosis #Dermatology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... - Differential Diagnosis ... Lemierre's syndrome ... Malignancy: - Hematologic ... tumors: Renal cell
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Leptospirosis ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Maculopapular - Diagnostic Algorithm Pathophysiology: - Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... red-flags to exclude dermatologic ... , vital sign instability ... - New-onset fever ... #Dermatology #Rash
Bradycardia - Differential Diagnosis Framework BRADI Mnemonic • BRASH/Hyperkalemia • Reduced oxygen/Glucose/Temp • ACS • Drugs •
- Differential Diagnosis ... Babesiosis • Leptospirosis ... Spondylarthropathies Other causes ... #differential #diagnosis ... #causes #cardiology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... mountain spotted fever ... #hematology #rheumatology ... #nonpalpable #dermatology
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
- Differential Diagnosis ... Stevens-Johnson Syndrome ... • Squamous cell ... MucousMembranes #dermatology ... #Algorithm #causes
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