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management differential dermatology erythematosus lupus sle symptoms oncology treatment classification pain vasculitis autoimmune disease hemophagocytic hlh joint leukemia lymphohistiocytosis mnemonic
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... #Diagnosis #Management ... #Hematology #Rheumatology
Fever Patterns - Differential Diagnosis Framework Continuous Fever: Temp > 38°C with only 1 degree fluctuation in 24
Differential Diagnosis ... Non-Infectious Causes ... • Leptospirosis ... Brucellosis Faget's Sign ... #Differential #Diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... mountain spotted fever ... #hematology #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... glomerulonephritis (>90%) S - Systemic ... CHAMPS #Mnemonic #diagnosis ... #differential #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic ... Leukemia cutis Diagnosis ... #diagnosis #dermatology
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #rheumatology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Differential Diagnosis ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... #Causes #hematology
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
region Viral Syndromes ... ; dengue shock syndrome ... capillary leak syndrome ... Infections: • Leptospirosis ... of malaria diagnosed
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Malar rash 40% - Fever ... Lupusreference #SLE #Systemic ... autoantibodies #signs ... #differential #rheumatology
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