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rheumatology erythematosus management sle systemic anemia aplastic behcet chronic classification cll dermatology differential disease emergencies fever fuo hemeonc lymphocytic mds
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... • CNS symptoms ... thin smear • Signs ... values supporting hematologic ... #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Sezary syndrome ... #diagnosis #workup ... #oncology #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... , breast CA - Hematologic ... - Lupus - Leukemia ... #diagnosis #dermatology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Hematology #Oncology ... #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... vein thrombosis Hematologic ... : • Symptoms limited ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... Usually myeloid leukemias ... #HemeOnc #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... virus (EBV) • Leukemia ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... tears, Ischemia, Leukemia ... #signs #symptoms ... #rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... age 70 years Symptoms ... Workup: • Complete ... #diagnosis #hematology ... #oncology
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