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rheumatology dermatology differential lupus dermatomyositis management symptoms vasculitis algorithm antimda5 antimda5dm antinxp2 antinxp2dm autoimmune classification clinical cold common compared complications
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
scaly annular lesions ... hair follicles -> causes ... inflammation on skin ... pathophysiology #diagnosis ... #signs #symptoms
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... Causes: - Idiopathic ... , breast CA - Hematologic
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
decades of life Causes ... lesions - Wheals ... Cold #Urticaria #diagnosis ... #rheumatology # ... comparison #table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Manifestations: Malar rash ... #comparison #table ... #rheumatology # ... diagnosis #management
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
Skin rash and malaise ... The signs and symptoms ... heaped, wart-like lesions—Condyloma ... resembling rashes caused ... #Diagnosis #Clinical
Erythemas Summarized Erythema ab igne • A dermatosis that results from repeated exposure to heat (fires, heating
centrifugum • A chronic skin ... classic targetoid lesions ... PrathitKulkarni #Erythemas #comparison ... #table #differential ... #diagnosis #dermatology
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Papulosquamous Skin ... Rash - Differential ... Diagnosis Algorithm ... Auspitz sign, Koebner's ... #Algorithm #causes
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... chest (in a V-sign ... lesions: antihelix ... #dermatology #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lesions • Mononeuritis ... tract, and often causes ... mucositis - Rash ... purpura: strong sign ... vasculitis, and SLE
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