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management differential clinical dermatology algorithm aptt lupus prolonged sle vasculitis classification coagulation cutaneous erythematosus oncology pt rash adultonset anemia aplastic
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
to Evaluate an Abnormal ... ) Step 3: Is a Systemic ... to identify the cause ... APTT #prolonged #diagnosis ... #hematology #evaluation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Destruction • Abnormal ... #Algorithm #Causes ... #Hematology
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... guidelines General - Systemic ... splenomegaly, abnormal ... cell disease Rheumatology ... Peds #Pediatrics #Diagnosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... Differential Diaqnoses ... solid cancers • Systemic ... Stills #Disease #diagnosis ... management #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... - CRP: Usually normal ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... associated with systemic ... amyloidosis #Abnormal ... #diagnosis #differential ... #hematology #coagulation
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... processes: • Systemic ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... associated with systemic ... Jcortesizaguirr #Abnormal ... #diagnosis #differential ... #hematology #coagulation
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... classification #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... fluid (CSF) is abnormal ... tract, and often causes ... #Rheumatology
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