37 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... symptoms of liver disease ... #differential #Diagnosis ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Liver Injury (DILI ... #gastroenterology ... #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... e.g. ascites), Chronic ... #Algorithm #hepatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Polycythemia Vera • Chronic ... : • Acute or Chronic ... disorders • Celiac disease ... effect following treatment
Management of Abdominal Distension and Bloating - Treatment Algorithm

Definitions
Pathophysiology
Organic/Pathologic Etiologies:
 • Small Intestinal Bowel Overgrowth (SIBO)
and Bloating - Treatment ... Intolerance • Celiac Disease ... Dyssynergia Diagnostics ... Bloating #Management #Diagnosis ... #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #diagnosis ... #algorithm #hepatology
The Liver Consult Primer - Guide to calling a consult
HPI:
 - Start with reason for consult
GTT, indirect bili ... current MELD - Chronic ... liver disease work ... Calling #Referral #Hepatology ... #Gastroenterology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... of SLE versus DIL ... life-threatening • Treatment ... • Evolution: Chronic ... disease Dr.
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... #Differential #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... • Evolution: Chronic ... disease Dr. ... #diagnosis #management