11 results
differential management druginduced sle vasculitis acute aki ana antibody antineutrophil antinuclear antiphospholipid apls classification comparison dil diseases erythematosus glomerulonephritis hematology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... + 90% • Granulomatosis ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... Purpura Anti-GBM antibodies ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... ) pattern: antibodies ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
- Differential Diagnosis ... Algorithm Acute ... Glomerulonephritis • Anti-GBM antibodies ... Pauci-immune (Granulomatosis ... #Algorithm #Causes
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... Algorithm Red ... • Anti-GBM antibodies ... Pauci-immune disease (Granulomatosis ... #Algorithm #Causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Summary Autoimmune ANCA ... (eosinophilic granulomatosis ... EGPA) • Auto-antibodies ... : ANCA antibody, ... #management #treatment
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup Algorithm ... maternal chromosomal causes ... excluded Testing: • Lupus ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
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