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diagnosis differential erythematosus sle systemic vasculitis antinuclear hematology algorithm autoantibodies table acr2021 classification diseases druginduced granulomatosis guidelines hemeonc patterns polyangiitis
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... Jcortesizaguirr #ANA ... #diagnosis #rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
ANA - Non-specific ... c-ANCA - Vasculitis ... Wegener's granulomatosis ... p-ANCA - Vasculitis ... #antibodies
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(ANA) ANA or Anti-NucIear ... • +ANA can be seen ... The higher the ANA ... • Pattern: The ANA ... #rheumatology #diagnosis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic Diseases ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Negative IF): • PR3-ANCA ... (C-ANCA): GPA > ... > eGPA • MPO-ANCA ... (P-ANCA): eGPA,
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Others: • Lupus ... such as systemic lupus ... LFT • ESR • ANA ... ) pattern: antibodies ... differential #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Management Summary ... Workup: - ANA ... life-threatening • Treatment ... Evolution: Chronic disease ... #Summary #rheumatology
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021
Granulomatosis with ... Polyangiitis (MPA) - ANCA ... Polyangiitis #MPA #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
small vessels - ANCA-associated ... - Wegener granulomatosis ... drugs, malignomas, and ... - systemic lupus ... Vessels #Diagnosis #Rheumatology
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... #Polyangiitis #ANCA ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
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