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diagnosis sle algorithm erythematosus hematology syndrome systemic neurology vasculitis causes guidelines acr2021 ana anca antinuclear disease druginduced granulomatosis oncology signs
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Antineutrophil cytoplasmic antibodies ... ) • Systemic lupus ... ANCA+ 90% • Granulomatosis ... Antineutrophil #antibodies ... #diagnosis #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Homogeneous: Systemic lupus ... , Drug-induced Lupus ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management • Giant Cell Arteritis (GCA) •
Guidelines for Treatment ... Nodosa (PAN) • Granulomatosis ... • Eosinophilic Granulomatosis ... #Treatment #ACR2021 ... Guidelines #algorithm #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... SLE-Related Auto-Antibodies ... (aPL) 30-45% Differential ... symptoms #mimickers #differential ... #rheumatology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Injury (AKI) - Differential ... Glomerulonephritis • Anti-GBM antibodies ... IgA, post-strep, lupus ... Pauci-immune (Granulomatosis ... legionella) • Immune (lupus
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... #Antinuclear #Antibodies ... ANA #patterns #rheumatology ... #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Post-strep GN, Lupus ... Purpura Anti-GBM antibodies ... Glomerulonephritis #Vasculitis #differential ... diagnosis #algorithm #rheumatology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
of Hematuria - Differential ... • Anti-GBM antibodies ... IgA, post-strep, lupus ... Pauci-immune disease (Granulomatosis ... #Hematuria #Differential
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
resulting from antibodies ... (aPL): • Lupus ... glycoprotein I antibodies ... to be present Treatment ... APS #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Diagnosis and Management ... , oral ulcers, Lupus ... life-threatening • Treatment ... #Summary #rheumatology
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