29 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #eosinophils #diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
anti-synthetase syndrome ... /full triad at diagnosis ... after 2 years of treatment ... Ann Marie Kumfer ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... severe disease Treatment ... Ann Marie Kumfer ... #SLE #Summary #diagnosis ... #rheumatology #
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
uric acid, LDH, Urine ... of the above Treatment ... of Clinical TLS ... monitoring • Consider ICU ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Renal Failure Treatment ... organ dysfuxtion, ICU ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... clinical manifestation ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
& Dry) is the treatment ... acute coronary syndrome ... & Dry” is the treatment ... heartfailure #chf #criticalcare ... #icu #clinical
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... of emergency, ICU ... #management #treatment ... #summary #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
> MICU, ♀, ↑Age ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis