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oncology vasculitis algorithm classification lymphoma syndrome treatment adultonset apml arteritis causes comparison conditions differentiation diffuse disease extrarticular gca giantcell glomerulonephritis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
involvement Differential ... Diagnosis of B-Symptoms ... • Other hematologic ... #differential # ... hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Immunohistochemical studies (to differentiate ... #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... Infectious • EBV ... Biopsy • Hodgkin's ... #Diagnosis #Algorithm ... #Causes #Hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
to Kidney: Anti-GBM ... With associated pulmonary ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Coxsackie, CMV, EBV ... hepatitis • Pulmonary ... #management #treatment ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... Hemopathies+++: Hodgkin ... Lymphohistiocytosis #diagnosis ... #management #treatment ... #summary #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Wilson's disease Pulmonary ... Spondyloarthropathies, SLE • Pulmonary ... ear, sparing the lobe ... #joint #pain #differential ... #diagnosis #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology ... #Management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... Diagnosis Framework ... progressing GN • New pulmonary ... glomerulonephritis) • Anti-GBM ... #diagnosis #rheumatology
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