29 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
workup, including BM ... hemolysis, deficiency anemia ... TPO, TPO-RA • Infections ... : Chronic infections ... bacterial and viral infections
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
feel weak": • Infectious ... : Influenza, EBV ... ILD, OSA, pHTN, Anemia ... illness, Infection ... ↓, Malignancy, Infection
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... Check For: • Infections ... Polyclonal IgM post infectious ... #hematology #diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Parenchyma • Infectious ... C, A, E, B, D, EBV ... Hepatitis, TPN • Infectious
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Drug-associated, PCH ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... circulation - Infections ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... #Causes #Hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... Opportunistic Infections ... opportunistic infections ... opportunistic infections ... opportunistic infections
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... Malignancies • Chronic infections
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... predictive of a serious infection ... overlook severe infections ... superior indicator of infection ... #WBC #CBC #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Neutropenia - recurrent infections ... Idiopathic • Infections ... #oncology #hematology ... #diagnosis #management