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differential causes workup anemia coagulation dermatology dic disseminated hemolytic intravascular leukocytosis management mds myelodysplasia myelodysplastic oncology pancytopenia petechiae physicalexam rash
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
malignancy: • ... lymphadenopathy, petechiae ... anemia, ↑ MCV, ↑/↓ platelets ... #Algorithm #hematology ... #WBC #Leukemoid
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... Algorithm Peripheral ... concerning for malignancy ... for workup, including ... #Algorithm #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... Algorithm Pinpoint ... Thrombocytopenia - Abnormal platelet ... deficiency Work ... #Algorithm #Causes
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Algorithm • 12 ... -13 g/dL, • ANC ... < 1800/uL, • platelet ... #Algorithm #hematology ... #workup
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Algorithm • Sickle ... with or without platelet ... valve, vasculitis, malignant ... #Algorithm #workup ... #hematology #testing
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
trauma, sepsis, malignancy ... promyelocytic leukemia ... Manifestations of DIC: • Petechiae ... #Coagulation #diagnosis ... treatment #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... caused by bleeding (petechiae ... Workup: • Complete ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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