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diagnosis differential nephrology causes management hypokalemia potassium treatment alkalosis metabolic workup criticalcare hyponatremia sodium cardiology chloride classification fever hypernatremia medications
Summary of Diuretic Agents Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP DIURETICS ... • Mannitol VASOPRESSIN ... Tolvaptan #Diuretics ... Pharmacology #summary #table
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia Algorithm ... Hyperglycemia, Mannitol ... , Medications (diuretics ... Primary polydipsia, Low ... #Hyponatremia #Algorithm
Increased Urination - Differential Diagnosis Framework - Increased Volume / Frequency • Increased osmotic load (Increased
load (Na, urea, mannitol ... • Physiologic Diuresis ... Post-obstructive diuresis ... urine (usually low ... Increased intake (low
Causes of Hypernatremia - Differential Diagnosis Algorithm Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L High
Differential Diagnosis Algorithm ... administration • Osmotic diuresis ... scheme) e.g., mannitol ... , glucosuria Low ... Differential #Diagnosis #Algorithm
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Diuretics and Agents ... (Mannitol) • ... Symport (Loop Diuretics ... ; High-Ceiling Diuretics ... #Medications #Table
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted - 2° hyperaldosteronism • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... , NGT suction, Low ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Differential #Diagnosis #Algorithm
Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
a.k.a. osmotic diuresis ... : Conventional diuretics ... gliflozins) • Other: Mannitol ... • Central Dl (Low
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... , NGT suction, Low ... Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Differential #Diagnosis #Algorithm
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... (AKI, Post-AKI diuresis ... Primary polydipsia), Low ... differential #diagnosis #table
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Loop and thiazide diuretics ... Hypokalemia - Osmotic diuresis ... Post-obstructive diuresis ... Differential #Diagnosis #Low ... #Magnesium #Table
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