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diagnosis differential causes nephrology hypokalemia pharmacology antiarrhythmics cardiology diuretics high hyperkalemia low alkalosis chloride disorders hematology hormones kidney locations lymphomas
Hormones Acting on the Nephron - Diuretics and Their Site of Action 1) Acetazolamide 2) Osmotic
Diuretics (e.g. mannitol ... ) 3) Loop Diuretics ... HCTZ) 5) Potassium-sparing ... spironolactone) #Pathophysiology
Diuretics - Pharmacology Thiazides diuretics: • Inhibit Na+ Cl- cotransporter in distal tubule • Chlorothiazide, Chlorthalidone, Indapamide,
Metolazone Loop ... Piretanide Potassium ... ), Isosorbide, Mannitol ... Pharmacology #nephrology #conversion ... #classes
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Extra-renal Losses ... • HTN Absent: Loop ... Differential #Diagnosis #Algorithm ... #causes #potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Hyperkalemia Differential Diagnosis Algorithm R/O Pseudo-hyperkalemia: • Possible Lab error! Alwavs Repeat Blood sample! • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Differential Diagnosis Algorithm ... Clinicians should also look ... differential #diagnosis #algorithm ... #potassium
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... : CLASS 1 - Sodium ... 3 - Potassium Channel ... #Pharmacology #Classification ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... : CLASS 1 - Sodium ... 3 - Potassium Channel ... #Pharmacology #Classification ... #Classes #pathophysiology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Dermatomyositis) AKI - Pathophysiology ... Monitor potassium ... Loop diuretics for ... Management #Summary #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
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