237 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Osmotic agents (mannitol ... Adenosine #Nephron
Hormones Acting on the Nephron - Diuretics and Their Site of Action
 1) Acetazolamide
 2) Osmotic
Acting on the Nephron ... Diuretics (e.g. mannitol ... Pathophysiology #Nephrology #Nephron
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
action on the nephron ... diuretics (e.g. mannitol ... triamterene) #nephron
Renal tubular acidosis (RTA): refers to a group of conditions all of which cause the same
conditions all of which cause ... different types/causes ... Diagnosis #IM #Nephro ... RenalTubularAcidosis #Features #Table
Polyuria - Differential Diagnosis
Solute Diuresis
 • Na intake/saline
 • Glucosuria: Hyperglycemia, SGLT-2 inhibitors
 • Urea: Exogenous
Resolution of AKI • Mannitol ... Differential #Diagnosis #Causes
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
DIURETICS • Mannitol ... Pharmacology #summary #table
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
Segments of the Nephron ... organic acids and bases ... vasopressin control #Nephron ... Pathophysiology #Tubules #Table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
loss through the nephron ... ), Isosorbide, Mannitol ... loop #thiazide #classes
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Causes of Hypernatremia ... scheme) e.g., mannitol ... Diagnosis #Algorithm #Causes
Dyspnea - Differential Diagnosis and Presentation

#Diagnosis #Differential #Table #Dyspnea #SOB #Causes
#Differential #Table ... #Dyspnea #SOB #Causes