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diagnosis hematology clinical differential echocardiogram pocus abnormal aptt prolonged pt a4c artery bleeding bruising cardiology cascade clot clotintransit clots comparison
This 24M presented with acute onset CP/SOB, hypoxia, HR 150s. What's the diagnosis? Treatment options? Hint:
presented with acute ... Thrombus in transit ... #Sign #PulmonaryEmbolism ... #Thrombus #Clots ... #InTransit
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 Clot in Transit on POCUS Echocardiogram Not something you ever want to see! How much should clot
Clot in Transit ... should clot in transit ... s4c #cardiology #thrombus ... #VTE #pulmonaryembolism ... #AcutePE
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 Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Congenital intrinsic ... coagulation factors ... Pre-analytical cause ... drugs e.g. direct thrombin
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
affected in the intrinsic ... Causes include : ... Pre-analytical cause ... drugs (e.g. direct thrombin ... differential #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation ... malignancy (Especially acute ... • Increased thrombin ... Treat primary cause ... #diagnosis #causes
Pulmonary Artery Clot seen on PSAX in Acute Saddle Pulmonary Embolism - Labeled Thrombus in Purple Suspicious
seen on PSAX in Acute ... Embolism - Labeled Thrombus ... for RV dilation, McConnell's ... The actual thrombus ... #Saddle #PulmonaryEmbolism
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 Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor of a coagulation ... • Warfarin • Acute ... discern these causes ... Liver disease • Acute ... warfarin, direct thrombin
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Review of the Coagulation ... extrinsic and intrinsic ... Initiation phase caused ... dependent upon intrinsic ... common pathway): Thrombin
Lactated Ringers (LR) vs Normal Saline (NS) - Comparison Composition of LR: • Sodium 130 mEq/L •
states such as acute ... shift • Saline Causes ... • Saline May Cause ... factors - impair coagulation ... impairment of thrombin
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