31 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
Leukemia) • GI diseases ... liver or kidney disease ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... / Symptoms: - ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
flexion of the knees ... While the pathophysiology ... for the hip/knee ... despite severe disease ... Clinical #Video #PhysicalExam
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
tears of gluteus medius ... Valgus position of knee ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
CLINICAL MANIFESTATIONS 
OF ADRENAL INSUFFICIENCY. 

Primary and secondary adrenal insufficiency:
 - Tiredness, weakness, mental depression
Primary and secondary ... Tiredness, weakness, mental ... eosinophilia Primary ... Autoimmune thyroid disease ... Insufficiency #Signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Primary Hyperthyroidism ... rare, gestational diseases ... Signs/Symptoms: ... Pretibial myxedema #Primary ... endocrinology #pathophysiology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... elbows/wrists and knees ... skin thickening Signs ... and Symptoms: ... Hepatic: PBC (primary
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... cases Clinical Signs ... years - May have signs ... decreased reflexes Pathophysiology ... CMC_IM #Potts #Disease
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... but elevated as disease
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... most commonly the knees ... AnkylosingSpondylitis #pathophysiology ... #diagnosis #signs ... #symptoms