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diagnosis differential causes clinical nephrology pathology plasmodium acute ain anemia blood bloodsmear borrelia falciparum fuo hemolytic identification infectiousdiseases interstitial microbiology
Plasmodium Falciparum Blood Smear. Key features suggesting Plasmodium falciparum: - extreme parasitemia - normocytic RBCs (vivax, ovale prefer big
Falciparum Blood Smear ... ~75% of human malaria ... cases - Banana-shaped ... peripheral #clinical #microscopy ... #microbiology #malaria
Plasmodium - Identification Algorithm • P. falciparum: RINGS AND GAMETOCYTES PREDOMINATE, Small delicate rings, <1/3 size
Identification Algorithm ... gametocytes • P. malariae ... Identification #Algorithm ... #pathology #smear ... #microscopy #malaria
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... triad (<10%): fever ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... Nephritis #AIN #Algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Differential Diagnosis Algorithm ... Peripheral blood smear ... Recent travel/Fevers ... Malaria, Clostridium ... Differential #Diagnosis #Algorithm
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Fever of Unknown ... Refer to your ‘Fever ... Returning Traveler’ algorithm ... • Travel to malaria–endemic ... Thick and thin smear
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Differential Diagnosis Algorithm ... • Exercise • Fever ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... Differential #Diagnosis #Algorithm
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Peripheral Blood Smear ... Northeast Africa with cases ... Several cases have ... sensitivity of blood smear ... recurrentis #BloodSmear #microscopy
Fever After International Travel Infectious Disease: • Endemic in either the destination or home region Viral Syndromes: Arboviral infections, a
falciparum: Most cases ... of malaria diagnosed ... • Falciparum malaria ... chest film; blood-smear ... dipstick test, microscopic
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