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diagnosis differential erythematosus msk pain sle systemic vasculitis approach workup comparison criteria cryoglobulinemia cryoglobulins eular eularacr monoarthritis monoarticular myopathies myopathy
Rheumatoid Arthritis - 2020 ACR-EULAR Classification ≥ 6 of 10 points = definite RA Joint Involvement:
Rheumatoid Arthritis ... 2020 ACR-EULAR Classification ... points Duration of symptoms ... #Rheumatoid #Arthritis ... #rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... • Arthritis domain ... in at least 2 joints ... pericarditis • Hematologic ... Erythematosus #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... of hip (rare), Arthritis ... Endocarditis, Aortic valve ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
spondyloarthropathies, lupus ... Lyme), reactive arthritis ... • Acute = Viral ... SLE, psoriatic arthritis ... #rheumatology #
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
with temporal arteritis ... Detectable HIV viral ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... diagnosis #comparison #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... • Inflammatory arthritis ... Noninflammatory arthritis ... bacterial, fungal, or viral ... #Pain #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... : • Joint pain ... Cytopenias • Cardiac valve ... : • Symptoms limited ... Erythematosus #Diagnosis #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Approach to Joint ... constitutional symptoms ... - Autoimmune Rheumatologic ... Viral Infections ... Diagnosis #MSK #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... cryoglobulin • Viral ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... such as systemic lupus ... Presentation - Systemic Symptoms ... differential #diagnosis #rheumatology ... #classification
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