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differential anemia microscopy blood bloodcell bloodsmear cell disorders dyspmorphic erythrocytosis essential et hemolytic hypercoagulable key macrocytic markers microcytic morphologies nomenclature
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases Acanthocyte (spur cell), Basophilic stippling, Bite cell,
Pathologic Red Blood ... Cell (RBC) Morphologies ... #RedBloodCell #Morphology ... Morphologies #Key #Atlas ... #Hematology #Diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
) Morphology Microcytic ... Chemotherapy (e.g ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... of substrate (e.g ... #Diagnosis #Workup ... #Hematology #Microcytic
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Disorder - Abnormal morphology ... bcr-able (+) ↑ WBC ... Polycythemia Vera (PV ... Blood #Disorders #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... other reproducible morphologic ... #Algorithm #workup ... #hematology #testing
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
• Provoked (e.g ... - No other workup ... cancer screening, CBC ... #hematology #diagnosis ... #algorithm #hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm Elevated Hemoglobin: • Males: Hb > 16.5 g/dL/HCT ≥ 49% •
Algorithm Elevated ... Paraneoplastic (e.g ... ., RCC, HCC, uterine ... Polycythemia #Vera #PV ... #Algorithm #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Management Summary ... incidentally via CBC ... • Treatment algorithms ... #Diagnosis #Management ... Summary #treatment #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
PV, MDS, CML) Treatment ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... Diagnosis? ... • CBC + diff • ... IFE, FLC assay Pathology ... #Workup #Hematology
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