22 results
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Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... hemolytic anemia ... hemolytic anemia ... #diagnosis #hematology ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... ) Morphology Atlas ... #Morphology #Atlas ... #key #diagnosis ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... uremic syndrome ... • Intrinsic RBC ... #hematology #anemia
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... 1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... FOR a cause → Systematic ... #Hemolytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... other reproducible morphologic ... elliptocytosis, autoimmune ... #workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Membrane): - Autoimmune ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... : Autoimmune, Microangiopathic ... hemolytic anemia ... Production #Index #hematology ... #diagnosis #calculation
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
- Differential Diagnosis ... , CKD • Hemolytic ... - Extrinsic: Autoimmune ... aciduria, Drugs (e.g ... #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... of substrate (e.g ... #Algorithm #Diagnosis ... #Workup #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... Inflammatory and Autoimmune ... Diseases: • Systemic ... #Hematology
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