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differential rheumatology management algorithm infectiousdiseases cardiology endocarditis neurology orthopedics thrombocytopenia anemia arthritis bee bone chronic classification cryofibrinogenemia cryoglobulinemia cryoglobulins deformity
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Causes of Fever ... • Infection: ... Lemierre's syndrome ... Malignancy: - Hematologic ... . autoimmune): Lupus
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... methotrexate) • Drugs Autoimmune ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Thrombocytosis): • Acute infection ... . autoimmune, TB ... Myelodysplastic syndrome ... #Causes #hematology
Inflammatory Joint Pain - Differential Diagnosis Algorithm Monoarticular • Gout (Podagra, Tophi) • Pseudogout • Early
- Differential Diagnosis ... Genitourinary Infection ... Sicca) Syndrome ... Inflammatory #JointPain #MSK ... #Orthopedics #Causes
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Causes of Knee Effusions ... - Differential Diagnosis ... Fever/Chills/Joint ... Acute rheumatic fever ... #msk #physicalexam
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Non-inflammatory Causes ... an underlying autoimmune ... Non-inflammatory causes ... skull neoplasms (e.g ... consistent with MS
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Malignancy Infectious ... Hepatitis • HIV Autoimmune ... Chronic Fatigue Syndrome
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... Constitutional disorders, eg ... neutropenia, Kostmann syndrome ... Chediak-Higashi syndrome ... #causes #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Autoimmune diseases ... Labs/Diagnosis: ... tissue disorder (e.g
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