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diagnosis management differential fungal infections microbiology candidemia fungemia fungi idsa infectiousdiseases invasive pathology aspergillus atrophicglossitis auris cglabrata common dermatology distribution
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
Invasive Candidiasis ... therapy First Line ... Targeted Treatment ... #IC #antifungal ... diagnosis #management #candida
IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days) Preferred
surface over the canine ... Note: Systemic antifungals ... for effective treatment ... #candida #mucosal ... IDSA #Prevention #Treatment
Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues Yeasts with Pseudohyphae: •
Morphology and Descriptions ... Consistent with Candida ... sometimes have this morphology ... differential #diagnosis #morphology ... septations #pathology #atlas
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues Broad-based budding yeasts: • Description: Broad-based
Morphology and Descriptions ... which are larger Morphology ... sometimes have this morphology ... differential #diagnosis #morphology ... #pathology #atlas
Candidemia Workup and Management - IDSA Guidelines 1) Antibiotics • Empiric: Echinocandins (e.g. micafungin) for most patients
Echinocandins (e.g ... central venous line ... Consider: Spine, ... Guidelines #Management #candida ... #candidiasis #treatment
Tongue Pathology Geographic tongue, fissured tongue, and hairy tongue are the most common tongue problems and
do not require treatment ... associated with a candidal ... responds to topical antifungals ... benign lesions (e.g ... examination of tongue morphology
Candida Glabrata Species of Candida Most Commonly Isolated in Bloodstream Infections • Symptomatic mucosal infection is detected
Candida Glabrata ... esophageal, & vaginal candidiasis ... unresponsiveness to antifungal ... Treatment: • Exhibits ... time to azole antifungals
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
immunosuppression (eg ... Non-pigmented (hyaline ... sometimes have this morphology ... Treatment: • ... Diagnosis #Management #treatment
Common Dermatological Conditions - Distribution and Morphology • Acne vulgaris - Face, upper back, chest -
Distribution and Morphology ... of erythema and scaling ... and pruritus (e.g ... hypopigmented macules • Candidiasis ... Varies with site, (e.g
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
six months of treatment ... Parvovirus B19 • Candida ... Calmette-Guérin (BCG ... by delaying ART treatment ... -6 weeks after antifungal
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