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Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
repeat testing • Acute ... proteinuria, RBC casts ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Differential Diagnosis of Acute Kidney Injury 

#Diagnosis #Nephrology #AKI #Acute #KidneyInjury #Causes #Differential #Workup #Algorithm #Ddxof
Differential Diagnosis ... of Acute Kidney ... #Nephrology #AKI ... #Causes #Differential ... #Workup #Algorithm
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
RBC casts in urine ... but in severe cases ... Nephritic #Nephrotic #Syndromes ... #Proteinuria #Nephrology ... #Diagnosis
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... PROBLEM ~80% of AKI cases ... for WBCs, RBCs, casts ... KidneyInjury #simplified #workup ... #diagnosis #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
suggestive of acute ... in a variety of acute ... suggestive of nephrotic sydnrome ... Urine #Microscopy #nephrology ... interpretation #diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic Syndrome ... nephrotic/nephritic syndromes ... hematuria (RBC casts ... Comparison #Algorithm #Nephrology ... #Diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... • Hepatorenal syndromes ... Epithelial cell casts ... #KidneyInjury #Nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... breakdown of cellular casts ... heme-granular casts ... edgarvlermamd - Nephrology ... #Nephrology
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
Red blood cell casts ... Red blood cell casts ... edgarvlermamd - Nephrology ... Comparison #Table #Nephrology ... #Diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... and Differential Diagnosis ... osmolarity If cause ... #nephrology #causes