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Morphology and Descriptions of Fungal Infections with Hyphae or Pseudohyphae in Tissues Yeasts with Pseudohyphae: •
other hyaline fungi ... Mucorales genera ... Consistent with Mucorales ... with dematiaceous fungi ... Pseudohyphae #fungal #fungi
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
cell response to fungi ... doesn't stain most fungi ... Aspergillus spp. and the Mucorales ... staining #diagnosis #fungi
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
difficile (gut) • Fungi ... Adenovirus, RSV • Fungi ... reactivation), RSV • Fungi ... differential #diagnosis #causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
component of many fungi ... Cryptococcus, Mucorales ... cut-offs defined in clinical ... - Negative: Mucorales ... closely related fungi
Endocarditis Algorithm - Infective vs Noninfective Causes Noninfective: • Malignancy • Autoimmune disease • Systemic infection Native Valve
vs Noninfective Causes ... Gram-negative bacilli • Fungi ... Gram-negative bacilli • Fungi ... #Noninfective #Causes
Morphology and Descriptions of Endemic Fungal Infections with Yeasts in Tissues Broad-based budding yeasts: • Description: Broad-based
other hyaline fungi ... Mucorales genera ... Consistent with Mucorales ... with dematiaceous fungi ... yeasts #fungal #fungi
1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
ß-D-glucan: • Most fungi ... Glucan-containing gauzes ... inconsistently in other fungi ... Diagnosis #Fungus #Fungi
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
Pathogenesis and clinical ... involved in >50% of cases ... S.A. can also be caused ... by, fungi, viruses
By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com @febrilepodcast] #ID #InfectiousDiseases #Infections #Microbiology #Micro #Cryptococcus #cryptococcosis
cryptococcosis #fungi ... #fungal #clinical
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood ... Tropheryma whipplei, Fungi ... febrilepodcast] #BCNIE #Causes ... differential #diagnosis #causes
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