62 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer's (99% of cases ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Opsoclonus-Myoclonus Ataxia Syndrome (OMAS) -Dancing eyes - dancing feet syndrome
 • Opsoclonus: ocular spontaneous, arrhythmic, conjugate
Opsoclonus-Myoclonus ... Ataxia Syndrome ... • Myoclonus: ... involuntary movements caused ... #Ataxia #Syndrome
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
Causes of Hemiplegia ... • Aphasia • Apraxia ... Acalculia • Alexia ... Cognition/Confusion, Dementia ... Diagnosis #Algorithm #Causes
Lateral Medullary Syndrome - Wallenberg's Syndrome
Acute continuous vertigo due to Posterior Circulation Stroke (usually Posterior Inferior
Clinical Findings: • Nausea ... • Ipsilateral ataxia ... tract • Palatal myoclonus
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
cause quadriplegia ... within GI and URT causes ... disseminates in blood ... fetal blood vessel ... peds #pediatrics #pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
Drug-induced edema is caused ... pressure in the blood ... potent effect on blood ... Edema #Medication #Causes ... #Pharmacology #Pathophysiology
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Alwavs Repeat Blood ... while drawing blood ... Diagnosis #Algorithm #causes ... potassium #high #pathophysiology
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Diagnosis and Pathophysiology ... Physiologic Causes ... Pathologic Causes ... Differential #Diagnosis #Pathophysiology ... #causes #cardiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • HIV dementia ... Pathophysiology ... integrity of the blood-brain ... penetrance through the blood-brain ... motor slowing and ataxia