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diagnosis differential neurology signs symptoms syndrome complications management alzheimersdisease anticonvulsants associated barre beriberi bulimianervosa cholesterol comparison deficiency disorder edema encephalopathy
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
Dose-dependent tremor, ataxia ... dizziness, diplopia, ataxia ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Lipoprotein Metabolism Enterocytes release absorbed lipids the form of triglyceride-rich chylomicrons. These are acted upon by endothelial
producing fatty acids ... The liver uses this ... VLDLs) and bile acids ... released into the blood ... Cholesterol #Metabolism #Pathophysiology
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
impairment • HIV dementia ... Pathophysiology ... integrity of the blood-brain ... motor slowing and ataxia ... #AIDS #Neurology
Hyperuricemia: Pathogenesis and Complications - Hypercalcemia (due to diseases like Sarcoidosis and Hyperparathyroidism) -> Accumulation of
acid from the blood ... acid and keto-acids ... acid from the blood ... Release of purine bases ... Hyperuricemia #Pathophysiology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... donor • Pathophysiology ... without other cause ... of ARDS to explain ... transfusion • Pathophysiology
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
plasma and some red blood ... epilepticus • Pathophysiology ... respiratory failure or ARDS ... The predominant pathophysiologic ... • Pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Collapse: • Pathophysiology ... electrolyte losses - Ataxia ... cardiomyopathy, ARDS ... muscle function, Ataxia ... differential #diagnosis #causes
Causes of Myoclonus - Differential Diagnosis LOCALIZATION: • Cortical: Focal/multifocal: Distal UL+ Face, Action/sensitive induced • Sub-Cortical:
Causes of Myoclonus ... degenerations, dementias ... acid-base, opioids, psychiatric ... MarcoMalaga97 #Myoclonus ... Differential #Diagnosis #Causes
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Summary Acute AIDP ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Opthaloplegia • Ataxia
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