10 results
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... without other cause ... : 33% • Treatment ... , and CXR with pulmonary ... : No • Treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Puncture, EEG Treatment ... CNS #neurology #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Phagocytosis of blood ... Drugs, Unknown cause ... Treatment: • ... #summary #rheumatology
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
• Most common cause ... Lung Abscess Pathophysiology ... anemia • Sputum/Blood ... Lung #Abscess #pulmonary ... #differential #causes
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... protein C and S Pathophysiology ... Treat primary cause ... #treatment #management ... #hematology
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Manifestations Causes ... increase venous blood ... HF • Moderate pulmonary ... Ophthalmoplegia - Ataxia ... beriberi #nutrition #pathophysiology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
Microbiology: Blood ... Cerebral > Splenic, Pulmonary ... Diagnosis: • Blood ... hematuria, + RF Treatment ... Diagnosis #cardiology #infectiousdiseases
Fusarium Infections
Acquired through:
1. Inhalation of airborne conidia > germinates > blood > disseminated
2. Trauma (implantation with
> germinates > blood ... Often isolated in blood ... Refractory FUO, Sino-pulmonary ... disease: • Optimal treatment ... Fusarium #Infections #infectiousdiseases
Hepatopulmonary Syndrome - Illness Script
HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... arteriovenous shunting causes ... mixed blood to ... the left heart TREATMENT ... only definitive treatment
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
symptoms • Rheumatologic ... • Major blood ... Aspergillosis Pathophysiology ... have positive blood ... ) #Mycoses #InfectiousDiseases