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diagnosis manifestations sle urology algorithm alzheimersdisease avascularnecrosis bulimianervosa cord dementia differential disorders erythematosus geriatrics incontinence mixed msk mucocutaneous musculoskeletal neuromyelitis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
/ Symptoms / Complications ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... pain • Extra-CNS complications ... disorders (Systemic lupus ... Manifestations #diagnosis #neurology ... #symptoms #signs
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... often- Sensory ataxia ... Non-compressive Spinal Cord Causes ... Blockage of the Blood ... disorders #diagnosis #neurology
Varicocele: Pathogenesis and clinical findings Primary: - Anatomically: the left spermatic vein drains into the left renal
artery Backup of blood ... retroperitoneal masses ... #Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incr PVR if a complication ... SUI or UUI not caused ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
) • Multiple causes ... therapy - Lupus ... AvascularNecrosis #pathophysiology ... #diagnosis #signs ... #symptoms
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
acids elevated blood ... hormone levels cause ... #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
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