18 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... / Symptoms / Complications ... Motor dysfunction: myoclonic ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Fits, Hemiplegia, Ataxia ... pain (20%) Renal disease ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... #symptoms #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
involvement: Intractable nausea ... pain • Extra-CNS complications ... disorders (Systemic lupus ... diagnosis #neurology #symptoms ... #signs
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
Sickle-cell disease ... Sickle cell disease ... The underlying pathophysiology ... Crisis #Features #Signs ... #Symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Decr delivery of blood ... inflammation tends to cause ... interstitial lung disease ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... retinal edema caused ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs ... #symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• The disease ... • Significant cause ... damage & blindness Signs ... / Symptoms / Complications ... ClosedAngle #Glaucoma #pathophysiology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
epidemiology of this disease ... history of the disease ... /Symptoms/Findings ... plasma cells in blood ... Agammaglobulinemia #XLinked #pathophysiology