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diagnosis differential sle behavioraldisorder complications erythematosus psychiatry rheumatology algorithm alzheimersdisease anxiety avascularnecrosis classification comparison cord dementia dermatology diffuse disorders edema
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Fits, Hemiplegia, Ataxia ... Demyelinating syndromes Heart ... Glomerulonephritis Myositis(5%) Blood ... erythematosus #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... Myopathy (Also caused ... #Lupus #Erythematosus ... Complications #pathophysiology ... #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... Motor dysfunction: myoclonic ... incontinence, apraxia ... AlzheimersDisease #Dementia #pathophysiology ... #symptoms
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework High Altitude Pulmonary Edema: • Accumulation
10,000 ft) • Symptoms ... central nervous system ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... /Symptoms: - Lightheadedness ... EMERGENCY • Multi-system ... differential #diagnosis #causes
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... endothelium) & Decr blood ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Differentiating NBTE from Infective Endocarditis No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs ... /symptoms or echo ... features: Fever -, Systemic ... features: Fever +, Systemic ... in up to 30% of cases
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Decr delivery of blood ... (Xerostomia) Heart ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... are not caused ... skin (16-32%): lupus ... posterior MSK, heart ... Diagnosis #Management #Signs
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
and signs below ... often- Sensory ataxia ... Non-compressive Spinal Cord Causes ... Blockage of the Blood ... , Scleroderma, Systemic
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