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Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
papules, pustules, necrosis ... Nodules, livedo, necrosis ... Identification of causes ... lesions #diagnosis #clinical
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
Avascular Necrosis ... Pathogenesis and Clinical ... ) • Multiple causes ... cells => Avascular Necrosis ... Sclerosis surrounding necrotic
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Pathogenesis and Clinical ... Viral replication causes ... - Palpable or necrotic
Vibrio Vulnificus skin infection Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. Vibrio vulnificus part of
marine microbiota & causes ... 10% Crab, few cases ... hemorrhagic bullae to necrotic ... Early abx are critical ... dermatology #legs #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Urticaria • Papulo-necrotic ... reticularis • Necrotic
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Etiology: • Necrosis ... • Most common cause ... Tissue necrosis ... Lung Abscess - Clinical ... #differential #causes
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
reactivity (Skin necrosis ... Cryofibrinogenemia Clinical ... ulcers • Skin necrosis ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
conditions that cause ... to pancreatic necrosis ... pregnancy, or other causes ... Clinical Significance ... a significant clinical
Chemical Eye Injury: Pathogenesis and clinical findings Exogenous chemical to the eye and/or adnexa • Ammonia, sodium
Pathogenesis and clinical ... Acidic injuries cause ... coagulative necrosis ... Alkali injuries cause ... disruptive liquefactive necrosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... reticularis & skin necrosis
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