31 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Pancytopenia - Differential ... Radiation • Drugs ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... Algorithm #Causes #Hematology
Baclofen Skin Rash

When a nursing home patient re-presents to the Emergency Department, go through their medication
Baclofen Skin Rash ... through their medication ... #Baclofen #Skin ... #Rash #Dermatology ... Allergy #Clinical #Photo
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... methotrexate) • Drugs ... Algorithm #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Non-hemolytic: ACD, Aplastic ... Orotic aciduria, Drugs ... MCV #Algorithm #Differential ... #Diagnosis #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Headaches • Pale skin ... - Antithyroid medications ... #hematology #diagnosis
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
Christmas Tree Rash ... parallel to lines of skin ... palms/soles - Differential ... rosea #clinical #dermatology ... #photo #PhysicalExam
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup and Differential ... Drugs Nutritional ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Diagnosis #Algorithm #Hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... Necrobiosis lipoidica Drugs ... • Bleomycin Hematologic ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Pancytopenia - Workup and Differential ... Drugs Nutritional ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... Diagnosis #Algorithm #Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
marrow failure: Aplastic ... anemia, Marrow ... suppression (e.g. drugs ... Production #Index #hematology ... #anemia #differential