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Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Compartment Syndrome, Medications ... Protein) • AIN: Medication ... Neurogenic Bladder (Medication ... Differential #Diagnosis #nephrology ... #causes #algorithm
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... trauma • Drugs ... GI losses • Renal ... • Reduced GFR, AKI ... #Nephrology #Differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... trauma • Drugs ... GI losses • Renal ... • Reduced GFR, AKI ... #Nephrology #Differential
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Framework PRE-Renal ... Congestion • Medications ... Infection-mediated, Drug-induced ... POST-Renal AKI ... Differential #Diagnosis #nephrology
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
Creatinine: • AKI ... , CKD • Medications ... nephroprotective ↓ in GFR • Medications ... Cystatin C: • AKI ... diagnosis #laboratory #nephrology
The Urine / Plasma Electrolyte Ratio - Guide to Fluid Restriction in Hyponatremia
 • U/P Ratio
The Urine / Plasma ... Restriction in Hyponatremia ... FR < 1000 mL + Medication ... MD @NephroMD #Urine ... diagnosis #management #nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... osmolarity If cause ... of AKI remains ... Differential #Diagnosis #nephrology ... #causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
there a dialysis indication ... require urgent nephrology ... obstruction, Nephrotoxic drugs ... IMPROVEMENT If the urine ... workup #diagnosis #nephrology
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
UOP/weights - Urine ... protein/Cr - Renal ... rhabdo/TLS) Causes ... #Nephrology #Diagnosis ... #Algorithm #Causes
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... of hypotonic hyponatremia ... volume-based algorithm Urine ... Losses (AKI, Post-AKI ... table #sodium #nephrology